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J P Kushner Selected Research

Porphyria Cutanea Tarda

7/2009Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases.
7/2009Longitudinal study of a mouse model of familial porphyria cutanea tarda.
12/2001Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
1/2001A mouse model of familial porphyria cutanea tarda.
12/2000Transdermal estrogen replacement therapy in postmenopausal women previously treated for porphyria cutanea tarda.
11/2000CYP3A-inducing agents and the attenuation of uroporphyrin accumulation and excretion in a rat model of porphyria cutanea tarda.

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J P Kushner Research Topics

Disease

6Porphyria Cutanea Tarda
07/2009 - 11/2000
5Hemochromatosis (Bronze Diabetes)
11/2006 - 03/2000
2Iron Overload
11/2006 - 01/2001
2Insulin Resistance
11/2006 - 07/2006
2Fibrosis (Cirrhosis)
11/2000 - 03/2000
1Eosinophilic Esophagitis
09/2014
1Genetic Predisposition to Disease (Genetic Predisposition)
09/2014
1Hypersensitivity (Allergy)
09/2014
1Porphyrias (Porphyria)
01/2001
1Skin Diseases (Skin Disease)
01/2001
1Anemia
01/2001
1Sickle Cell Anemia (Hemoglobin S Disease)
01/2001
1Iron Deficiencies
01/2001
1Refractory Anemia
01/2001
1Thalassemia
01/2001
1Liver Cirrhosis (Hepatic Cirrhosis)
11/2000
1Joint Diseases (Joint Disease)
11/2000
1Inflammation (Inflammations)
03/2000

Drug/Important Bio-Agent (IBA)

5IronIBA
07/2009 - 03/2000
3Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)IBA
07/2009 - 01/2001
2Glucose (Dextrose)FDA LinkGeneric
11/2006 - 07/2006
2Insulin (Novolin)FDA Link
11/2006 - 07/2006
1AntigensIBA
09/2014
1RNA (Ribonucleic Acid)IBA
09/2014
1CytochromesIBA
07/2009
1PorphyrinsIBA
01/2001
1Iron Chelating AgentsIBA
01/2001
1Oral ContraceptivesIBA
12/2000
1TransferasesIBA
11/2000
1Transferrin (beta 2 Transferrin)IBA
11/2000
1Polychlorinated Biphenyls (PCBs)IBA
11/2000
1Chlorodiphenyl (54% Chlorine)IBA
11/2000
1Aminolevulinic Acid (Levulan)FDA Link
11/2000
1Drinking WaterIBA
11/2000
1Estrogens (Estrogen)FDA Link
03/2000

Therapy/Procedure

1Chelation Therapy (Therapy, Chelation)
01/2001
1Therapeutics
01/2001
1Estrogen Replacement Therapy
12/2000